Bacterial nanoplatform reprograms spleen immune cells to help prevent cancer recurrence

A research team led by Professor Yong Taik Lim at the SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, have developed an engineered nanoplatform named t-SMC (trained immunity-mediated splenic myelopoiesis converter), which precisely targets the spleen to reverse splenic myelopoiesis toward an antitumoral immune phenotype. The research is published in the journal Advanced Materials.